K325 / 2027

Lesson 3 of 12 / Reproduction

Meiosis halves the chromosome number

How is meiosis different from mitosis?

In this lesson: Explain the reduction in chromosome number and the role of meiosis in gamete formation.

About 5 min

The key ideaMeiosis separates homologous chromosomes and halves the chromosome number, producing genetically dissimilar haploid cells.

Meiosis reduces four chromosomes to two in each haploid cellDiploid parent: 2n = 4Predict the number in each new cell
The model species has two homologous pairs: one long pair and one short pair.

Bars stand for chromosomes; DNA copying and division stages are omitted to focus on sets. The meiosis model isolates assortment without crossing over, so some products shown match. It is not a diagram of four equally developed human egg cells.

Explanation

Meiosis begins with a diploid cell and, after DNA copying and two divisions, produces haploid cells. The separation of homologous chromosomes in the first division reduces the number of chromosome sets from two to one.

The chromosome combinations differ among the resulting cells. The sorting of homologous pairs, together with exchange of genetic material, creates variation. Detailed stages and crossing-over mechanisms are not required for this outline.

Meiosis is used in the formation of gametes. Fertilisation then restores the diploid number. In animals, the resulting cells develop into gametes; diagrams showing four cells should not be read as four equally developed human egg cells.

The key contrast is the outcome: mitosis gives matching nuclei with the original chromosome number, while meiosis gives genetically different haploid cells with half that number. Use both chromosome number and genetic similarity in a comparison.

Step by step
  1. 1

    Start with homologous pairs

    A diploid starting cell has one member of each pair from each parent.

  2. 2

    Separate the pairs

    Each haploid set receives one chromosome from each pair.

  3. 3

    Connect to fertilisation

    Combining two haploid nuclei restores the diploid number in the next generation.

Worked example

Explain variation

Two sperm cells from the same individual can contain different inherited information. Explain why.

One way to explain it

Meiosis produces haploid cells with different combinations of genetic information. Each sperm receives one chromosome set, but the alleles within those sets need not be identical.

Why this answer works
  • Same parent does not mean identical gametes.
  • The number is the same even though the genetic combinations can differ.
Is this true? "Meiosis makes cells with random numbers of chromosomes."

Normal meiosis halves the chromosome number consistently. The combinations of inherited information vary, not the required number of sets.

Try a question

A diploid nucleus has 12 chromosomes. What is the normal result of meiosis?
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