K325 / 2027

Lesson 2 of 12 / Reproduction

Gametes and chromosome sets

What do haploid, diploid and homologous mean?

In this lesson: Define sexual reproduction and explain chromosome sets before and after fertilisation.

About 5 min

The key ideaHaploid gametes carry one chromosome set each; their nuclei fuse to form a diploid zygote.

Two haploid gamete nuclei each contain two complete chromosomesHaploid: n = 2Haploid: n = 2One complete set in each nucleus
Each gamete contains one long and one short chromosome. Haploid means one set, not chromosomes cut into fragments.

A model species with four diploid chromosomes. In humans, the usual numbers are 23 + 23 = 46.

Explanation

Sexual reproduction involves fusion of the nuclei of a male and a female gamete to form a zygote. Offspring are genetically dissimilar because they receive a new combination of inherited information.

A diploid nucleus has two sets of chromosomes, one inherited from each parent. Its chromosomes can be arranged in homologous pairs. Members of a pair have corresponding genes at the same positions, although the versions of those genes can differ.

A haploid nucleus has one set: one chromosome from each homologous pair. Human body-cell nuclei usually have 46 chromosomes, while sperm and egg nuclei have 23. A haploid set is not half a chromosome; it contains complete chromosomes.

During fertilisation, 23 chromosomes from each human gamete combine to give the diploid 46 in the zygote. A reduction division before fertilisation prevents chromosome number doubling in each generation.

Homologous does not mean genetically identical. The two members of a pair may carry different alleles. Also distinguish homologous chromosomes from the matching copied parts of one duplicated chromosome.

Step by step
  1. 1

    Count sets, not drawing arms

    A diploid cell has two sets even when the artist draws chromosomes as rods rather than X shapes.

  2. 2

    Match homologous pairs

    Look for corresponding genes and positions, not necessarily identical alleles.

  3. 3

    Restore the diploid number

    Add the two haploid contributions at fertilisation.

Worked example

An imaginary species

A species has a diploid number of 8. Predict its gamete and zygote chromosome numbers.

One way to explain it

Each gamete is haploid and has 4 chromosomes. Fusion of two gamete nuclei restores 8 in the diploid zygote.

Why this answer works
  • The diploid number is halved before fertilisation.
  • Fertilisation combines complete haploid sets: 4 + 4 = 8.
Is this true? "A homologous pair always contains two identical versions of every gene."

The chromosomes carry the same genes at corresponding positions, but their alleles can differ.

Try a question

Why must chromosome number be reduced before gamete nuclei fuse?
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