K325 / 2027

Lesson 7 of 10 / Inheritance

The usual XX and XY model

Which gamete contribution distinguishes XX from XY?

In this lesson: Use a genetic diagram to explain the usual chromosomal determination of sex in humans.

About 4 min

The key ideaIn the usual XX/XY model, eggs carry X while sperm carry X or Y. Fertilisation gives an expected 1:1 ratio of XX to XY.

Which chromosome comes from each gamete?

Use the usual XX parent and XY parent. Choose a possible offspring combination below.

XXXYXXXX
Choose a box: combine the egg and sperm sex chromosomes
GametesXY
X

Expected outcomes: XX (usual female): 1/2; XY (usual male): 1/2

Rows: egg sex chromosome. Columns: possible sperm sex chromosomes. Boxes are equally likely combinations for the stated crosses, not a required sequence of offspring. Repeated genotypes can occur in different boxes. This shows the usual XX/XY model; real sex development can have biological variations.

Explanation

The usual human chromosomal model describes females as XX and males as XY. The other chromosomes are autosomes. Sex-chromosome inheritance can be followed using the same gamete-combination method as other genetic diagrams.

An XX parent produces eggs carrying one X chromosome. An XY parent produces sperm carrying either X or Y, with roughly equal probability in this simple model. Every gamete also carries a set of autosomes.

An X-bearing sperm combining with the egg gives XX, while a Y-bearing sperm gives XY. The expected ratio is 1 XX : 1 XY. The sperm contribution distinguishes the two outcomes, but it is a chance process rather than a decision or a reason to blame either parent.

An expected 1:1 ratio does not guarantee equal numbers in a small family or an alternating sequence. This is the usual syllabus model of chromosomal sex determination; actual sex development can involve biological variations beyond this simplified diagram.

Step by step
  1. 1

    State parental chromosomes

    Use XX and XY for the usual model.

  2. 2

    List gamete contributions

    The egg carries one X; a sperm carries either X or Y.

  3. 3

    Combine and interpret

    Give XX or XY and an expected equal probability under the model.

Worked example

Another child in the model

A family already has two XY children. Under the simple model, what is the probability of XX in another fertilisation?

One way to explain it

The probability remains 1/2. An X-bearing or Y-bearing sperm can fertilise the X-bearing egg independently of the previous outcomes.

Why this answer works
  • Previous children do not change the egg contribution.
  • The next gamete combination is a separate chance event.
Is this true? "The egg must switch between X and Y to balance a family."

In the usual model eggs carry X. Sperm carry X or Y, and earlier outcomes do not force the next one.

Try a question

Which combination produces XY in the usual human model?
You can return to this lesson any time.