K325 / 2027

Lesson 1 of 10 / Homeostasis and response

Negative feedback

How does a correction know when to ease off?

In this lesson: Build a negative-feedback explanation from a change in the internal environment.

About 5 min

The key ideaHomeostasis maintains a relatively constant internal environment. Negative feedback produces a response that opposes a change.

An internal condition, such as blood glucose concentration, is a variable. It normally fluctuates within a narrow range rather than staying at one exact value.

Does the response oppose the change?
Usual rangeLowerHigherResponse opposes change

Brown dot: internal condition. Green band: usual range. Arrow: effect of the corrective response.

  1. Receptors detect the change.
  2. A coordinating centre directs effectors.
  3. The response reduces the deviation.

Explanation

Cells work best within suitable internal conditions. Homeostasis maintains these conditions despite changes inside or outside the body. Examples include body temperature, blood glucose concentration and the water potential of the blood.

A change in a condition acts as a stimulus. Receptors detect it, a coordinating centre processes the information, and effectors carry out a corrective response. An effector may be a muscle or a gland. Name each part when the question supplies it.

In negative feedback, the response opposes the original change. If a condition rises above its usual range, the response lowers it. If it falls below the range, a different response may raise it. Negative means opposing the change, not harmful.

As the condition returns towards its normal range, the stimulus becomes smaller and the corrective response decreases. This prevents continuous overcorrection. A response that makes the original change larger is not negative feedback.

Step by step
  1. 1

    State the change

    Say which internal condition rose or fell relative to its normal range.

  2. 2

    Trace the correction

    Name the detector, coordinating centre and effector if they are known.

  3. 3

    Close the loop

    Explain how the response opposes the change and then decreases as the condition is restored.

Worked example

Recognising feedback

Body temperature rises. Sweating increases, and temperature then falls towards normal. Why is this negative feedback?

One way to explain it

The cooling response opposes the initial rise in temperature. As temperature returns towards normal, the stimulus for increased sweating decreases.

Why this answer works
  • Identify the initial rise.
  • Link sweating to cooling, which acts in the opposite direction.
  • Include the reduction in the corrective response.
Is this true? "Homeostasis keeps every internal condition completely unchanged."

Conditions fluctuate within a narrow range. Homeostatic responses limit the deviations; they do not stop all change.

Try a question

Which sequence shows negative feedback?
You can return to this lesson any time.