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The Mole Concept and Stoichiometry

Topic 1 of 3

Particles to formulae

Separate mass ratios from atom ratios.

A-Level 8873, revised syllabus (2026-2027)

Keep relative mass, molar mass and amount distinct

Relative quantities have no units; molar mass converts grams into moles.

Relative masses compare a mass with one twelfth of the mass of a carbon-12 atom. They are ratios, so they have no unit. Relative isotopic mass refers to one isotope; relative atomic mass, Ar, is the weighted mean for the atoms in a specified sample of an element.

Four mass terms
TermWhat is compared with one twelfth of a carbon-12 atom
Relative isotopic massMass of one atom of the stated isotope
Relative atomic mass, ArWeighted mean mass of atoms of the element
Relative molecular mass, MrMass of one molecule; numerically the sum of its constituent Ar values
Relative formula mass, MrMass for one formula unit; the sum of Ar values in that formula, used for ionic compounds

One mole contains exactly 6.02214076 × 1023 specified entities. The Avogadro constant NA is that number per mole, with unit mol-1. Specify whether you mean atoms, molecules, ions, electrons or formula units. One mole of MgCl2 formula units contains one mole Mg2+ ions and two moles Cl- ions.

Use n = m/M for mass m in g and molar mass M in g mol-1; n is in mol. M has the same numerical value as the corresponding Ar or Mr, but different units. For particles, N = nNA.

Worked example

Weight the isotope data

A sample contains 75.0% isotope mass 35.0 and 25.0% isotope mass 37.0. Calculate its relative atomic mass using the supplied rounded isotopic masses.

  1. Convert percentages into fractions: 0.750 and 0.250.
  2. Weighted mean = (0.750 × 35.0) + (0.250 × 37.0).
  3. The result is 35.5; it lies between the two isotope masses and nearer the more abundant one.
Answer

Ar = 35.5, with no unit. An unweighted average of 36.0 would incorrectly treat the isotope populations as equal.

Worked example

From a weighed sample to atoms

How many atoms are in 0.486 g Mg, using Ar(Mg) = 24.3?

  1. n = 0.486 g / (24.3 g mol-1) = 0.0200 mol.
  2. N = 0.0200 mol × 6.02214076 × 1023 mol-1.
Answer

1.20 × 1022 Mg atoms, to three significant figures.

Turn mass evidence into an atom ratio

An empirical formula is the simplest ratio; a molecular formula counts atoms in one molecule.

An empirical formula gives the simplest whole-number ratio of elements. A molecular formula gives the actual number of each atom in one molecule. Ethene has molecular formula C2H4 and empirical formula CH2. Ionic substances such as MgO have formula units rather than discrete molecules.

Composition-by-mass method
  1. Choose a basis

    For percentages, imagine 100 g. Each percentage then becomes a mass in grams.

  2. Convert each element to moles

    Divide its mass by its atomic molar mass.

  3. Divide by the smallest

    Obtain the simplest mole ratio, not a mass ratio.

  4. Reach whole numbers carefully

    A reliable ratio such as 1:1.5 must be doubled, not rounded to 1:2.

Worked example

A percentage formula with a fractional ratio

An oxide contains 69.9% Fe and 30.1% O. Use Ar(Fe) = 55.8 and Ar(O) = 16.0.

  1. For 100 g, Fe amount = 69.9/55.8 = 1.253 mol; O amount = 30.1/16.0 = 1.881 mol.
  2. Divide both by 1.253: approximately 1 : 1.50.
  3. Multiply both values by two: 2 : 3.
Answer

The empirical formula is Fe2O3. The small departures from an exact ratio reflect the rounded input data.

Worked example

Use combustion and mass by difference

Complete combustion of 0.900 g of a compound containing only C, H and O gives 1.320 g CO2 and 0.540 g H2O. Its Mr is 90.0. Find both formulae; use C = 12.0, H = 1.00, O = 16.0.

  1. CO2 amount = 1.320/44.0 = 0.0300 mol, so C amount = 0.0300 mol and C mass = 0.360 g.
  2. H2O amount = 0.540/18.0 = 0.0300 mol. There are two H atoms per water molecule, so H amount = 0.0600 mol and H mass = 0.0600 g.
  3. Original O mass = 0.900 - 0.360 - 0.0600 = 0.480 g; O amount = 0.480/16.0 = 0.0300 mol.
  4. C:H:O = 0.0300:0.0600:0.0300 = 1:2:1, so the empirical formula is CH2O.
  5. Empirical formula mass = 30.0. The multiplier 90.0/30.0 = 3.
Answer

Empirical formula CH2O; molecular formula C3H6O3.

Check your understandingDoes an empirical formula of CH2 uniquely identify ethene?Think it through, then reveal the answer
No. C2H4, C3H6 and other molecules can share that simplest ratio. A relative molecular mass or other independent evidence is needed.