K327 / K328 / 2027

Lesson 3 of 7 / Transport in humans

What blood carries

Why does blood need both red cells and liquid plasma?

In this lesson: Match oxygen and other transported materials to the relevant blood component.

About 4 min

The key ideaHaemoglobin in red blood cells carries most oxygen; plasma carries the cells and many dissolved substances.

Compare the red cell in
Oxygen bound to haemoglobin: loading in lungsPlasmaOxygen binds to haemoglobinRed blood cell
Oxygen binding is reversible. Compare where oxygen is loaded and where it is released; the circle counts are only a teaching model.

Explanation

Blood has a liquid part, plasma, with red blood cells, white blood cells and platelets suspended in it. Each component contributes a different function; blood is not just a liquid containing oxygen.

Red blood cells contain haemoglobin, which combines reversibly with oxygen to form oxyhaemoglobin. In the lungs, abundant oxygen favours loading. In respiring tissues, a lower oxygen concentration favours release.

A red blood cell has a biconcave shape, giving a large surface area relative to its volume and a short diffusion distance. It has no nucleus when mature, leaving more space for haemoglobin. Its flexibility helps it pass through narrow capillaries.

Plasma transports blood cells and dissolved ions, soluble food substances such as glucose and amino acids, vitamins, hormones, urea and plasma proteins. Much carbon dioxide is carried in the plasma after conversion into dissolved bicarbonate ions; the detailed chemistry is not needed here.

These journeys have destinations: glucose moves from absorption sites towards cells, hormones towards target organs, and urea from the liver towards kidneys. Oxygen transport is mainly associated with haemoglobin, not simply dissolved in plasma.

Step by step
  1. 1

    Choose the component

    For most oxygen, name red blood cells and haemoglobin. For many dissolved materials, name plasma.

  2. 2

    Locate loading and unloading

    Explain where the substance enters the blood and where it is used or removed.

  3. 3

    Link structure to function

    For red cells, explain surface area, diffusion distance or room for haemoglobin.

Worked example

Two different deliveries

Compare how blood carries oxygen from the lungs and urea from the liver.

One way to explain it

Most oxygen is carried bound to haemoglobin in red blood cells and released in tissues. Urea is dissolved in plasma and transported from the liver to the kidneys for excretion.

Why this answer works
  • Name a different carrier for each substance.
  • Urea is a nitrogenous waste, not an oxygen carrier.
  • Transport does not mean the substance is used at its destination: kidneys remove urea.
Is this true? "Deoxygenated blood contains no oxygen and turns blue."

It contains less oxygen and is dark red. Blue in diagrams is a convention that makes routes easier to distinguish.

Try a question

A hormone and urea are travelling in blood. Which component mainly transports both?
You can return to this lesson any time.